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Lasers have been used in medicine for decades, and depending on the wavelength, energy level and treatment time, can be used to cut, cauterise, destroy tissue and control pain by altering cellular function. Using lasers to "zap" fat, however, is a relatively new concept. Paddles containing a low-level, 635-nanometre laser are placed over regions of unwanted fat. While a small amount of the light is absorbed by the skin, the majority of the energy penetrates through to adipose tissue beneath. Here, bunches of grape-like fat cells attached to the skin absorb light energy from the laser, triggering a cascade of biochemical reactions that ends up with the cells rupturing. Here, Thomson compares zapping fat with lasers with other fat loss measures.