"Ormsbee MJ, Choi MD, Medlin JK, Geyer GH, Trantham LH, Dubis GS, Hickner RC. Regulation of fat metabolism during resistance exercise in sedentary lean and obese men," scientists writing in the Journal of Applied Physiology report (see also
"J Appl Physiol 106: 1529-1537, 2009. First published March 5, 2009; doi:10.1152/japplphysiol.91485.2008.-The effect of acute resistance exercise (RE) on whole body energy expenditure (EE) and alpha(2)-adrenergic receptor (alpha(2)-AR) regulation of lipolysis in subcutaneous abdominal adipose tissue (SCAAT) was determined in sedentary lean (LN) and obese (OB) men. Lipolysis was monitored using microdialysis in 10 LN [body mass index (BMI) 20.9 +/- 0.6] and 10 OB (BMI 36.2 +/- 2.7) men before, during, and for 24 h after RE. EE was measured before and immediately after RE for 40 min. Changes in interstitial glycerol were measured in SCAAT with three microdialysis probes perfused with a control solution, phentolamine (alpha(2)-AR antagonist), or propranolol (beta-AR antagonist). EE and fat oxidation (FOX) were significantly (P < p =" 0.03)" p =" 0.002)." p =" 0.002)" p =" 0.03)">
The researchers concluded: "The blunted SCAAT lipolytic response to RE in OB compared with LN men is unrelated to RE-induced catecholamine activation of the antilipolytic alpha(2)-ARs and may be due to depressed GH in OB subjects.."
Ormsbee and colleagues published their study in the Journal of Applied Physiology (Regulation of fat metabolism during resistance exercise in sedentary lean and obese men. Journal of Applied Physiology, 2009;106(5):1529-1537).
Additional information can be obtained by contacting R.C. Hickner, East Carolina University, Human Performance Laboratory, College Health & Human Performance, Dept. of Exercise & Sport Science, 363 Ward Sports Med Bldg, Greenville, NC 27858, USA.
The publisher of the Journal of Applied Physiology can be contacted at: American Physiological Society, 9650 Rockville Pike, Bethesda, MD 20814, USA.
Keywords: United States, Greenville, Antihypertensive, Applied Physiology, Bariatrics, Diabetes, Dialysis, Drugs, Gastroenterology, Metabolism, Microdialysis, Microtechnology, Obesity, Pharmaceuticals, Phentolamine, Propranolol Hydrochloride, Sympatholytic, Therapy, Treatment, East Carolina University.
